Michael Wu , MD

Email: mcwu@fredhutch.org

Phone: (206) 667-6603

Dr. Shi has a broad background and specific expertise in protein engineering, gene expression regulation, and signal transduction in disease settings. At the University of Washington School of Medicine, Dr. Shi has expanded his research to include proteomics-based discovery and targeted validation of candidate proteins in in vitro models. He has also led or critically involved in projects to apply the proteomic discovered and other important proteins as biomarkers for neurodegenerative disorders such as Parkinson disease and Alzheimer disease

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Peter Wu , MD

Email: pcwu@u.washington.edu

Phone: (206) 768-5287

Dr. Wu maintains a funded translational surgical oncology research laboratory based at the VA Puget Sound supported by a VA SIBCR faculty award and VA Merit Career Development Award. His research group primarily studies the role and impact of cellular senescence and senescence escape on advanced GI malignancies in response to cancer treatment such as chemotherapy. He is the principal investigator for the VA Puget Sound Gastrointestinal Tumor Tissue Repository, which serves to support translational cancer research and encourage interdisciplinary collaborations.

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Fei Xia , PhD, MS

Email: fxia@u.washington.edu

Phone: (206) 543-9764

Dr. Xia's research area is computational linguistics. Her research covers a wide range of NLP tasks including morphological analysis, part-of-speech tagging, grammar extraction and grammar generation, treebank development, machine translation, named-entity recognition, and information extraction.

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Li Xin , PhD

Email: xin18@uw.edu

Phone: (206) 543-6551

Dr. Xin's lab is interested in using the prostate as a tissue model to study the molecular and cellular mechanisms that regulate development, tissue homeostasis and carcinogenesis. Currently, there are two major research focuses in the lab. The first is to characterize the prostate epithelial lineage hierarchy and investigate how individual prostate epithelial lineages are maintained in adults by prostate stem cells and to identify master regulators that control adult prostate homeostasis. The is to investigate the molecular and cellular basis of aggressive prostate cancer. The lab is interested in determining the function of disease-associated genes in prostate cancer initiation and progression, and characterizing the identity of the cells of origin for prostate cancer. The major approaches utilized are cell culture-based prostate stem cell assays, genetically engineered mouse models, and a prostate regeneration method.

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Xiaoming Yang , MD, PhD, FSIR

Email: xmyang@uw.edu

Phone: 206-685-6967

Dr. Yang is a UW professor and director of image-guided bio-molecular interventions research in the Department of Radiology at the University of Washington School of Medicine. Dr. Yang has created several new concepts and technologies on medical imaging and interventional radiology in the world, including developments of intraluminal MR imaging and interventions, MRI-tracking of stem cells in vascular diseases, imaging of vascular gene therapy, and interventional molecular imaging.

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Ka Yee Yeung , PhD

Email: kayee@uw.edu

Phone: (253) 692-4924

Dr. Yeung has extensive experience in the design of algorithms for the mining and integration of big data. She also has research expertise/interest spanning multiple disciplines, including computer science, statistics, computational biology, cancer biology and systems biology.

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Matthew Yeh , MD, PhD

Email: myeh@u.washington.edu

Phone: (206) 598-0008

Dr. Yeh interests in studying the pathology and pathogenesis of non-alcoholic fatty liver disease (NAFLD); Tumorigenesis of liver and pancreas; Pathogenesis of chronic viral hepatitis B and C; Transplantation pathology of liver; and Pathology of gastrointestinal tracts. Dr. Yeh serves as a pathologist at UW gastroenterology clinic.

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Cathy Yeung , PhD, PharmD

Email: cathyy@u.washington.edu

Phone: (206) 897-4709

Dr. Yeung's research includes both basic science and translational studies, and spans from the determination of molecular mechanisms of altered drug metabolism using 3-dimensional cell culture techniques to the evaluation of the effect of drugs and nutritional supplements on health outcomes in patients receiving hemodialysis. She is also involved in the development of a kidney on a chip microphysiological system that can be used in preclinical drug toxicity screening.

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Raymond Yeung , MD

Email: ryeung@u.washington.edu

Phone: (206) 616-6408

Dr. Yeung is a surgeon whose focus is the treatment of liver and bile duct tumors. His research focuses on the genetic mechanisms of tumorigenesis with emphasis on tumor suppressor genes and hereditary cancers. Dr. Yeung's work exploits a unique animal model of hereditary cancer to study the multi-step process of tumor development. Two such novel tumor suppressor genes of current interest relate to the disease tuberous sclerosis complex (TSC). Dr. Yeung's laboratory utilizes genetic, cell biologic and biochemical approaches to dissect the function of these genes.

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Cecilia Yeung , MD

Email: cyeung@seattlecca.org

Phone: (206) 288-7104

Dr. Yeung’s primary research interest is in molecular profiling of Myelodysplastic Syndromes.

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Janet Young , PhD

Email: jayoung@fredhutch.org

Phone: (206) 667-4512

Dr. Young's graduate work was performed in Sue Povey's lab, looking at the genetic basis for a human genetic disease called tuberous sclerosis. This was followed by twelve years working with Barbara Trask in Fred Hutchinson's Human Biology division, first as a post-doc and then as staff scientist. There, her research mostly focused on the evolution and transcriptional regulation of some very large mammalian gene families' olfactory and vomeronasal (pheromone) receptors. Young also applied her bioinformatics skills to a number of other projects in the Trask lab, including copy-number gain and loss in prostate cancer and measurement of methylation levels across the human genome.

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Evan Yu , MD

Email: evanyu@u.washington.edu

Phone: (206) 288-6292

Dr. Yu, a medical oncologist, treats prostate, bladder and testicular cancer, and is passionate about providing a personalized medicinal approach to a selection of novel therapies as well as understanding biologic mechanisms of drug sensitivity and resistance.

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Bo Yu , MD, MS

Email: by26@uw.edu

Phone: (206) 221-8279

Dr. Yu is board certified both in OB/GYN and in reproductive endocrinology and infertility. Her clinical interests include reproductive care in cancer patients, female infertility, and reproductive endocrinology.

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William Yuh , MD

Email: wyuh@uw.edu

Phone: (206) 543-3320

Dr. Yuh's interests and expertise are in advanced imaging for diagnosis and imaging-guided treatment of various disease entities, imaging-based disease heterogeneity, and optimizing efficacy of imaging contrast agents. During the early development phase of the magnetic resonance (MR) contrast agents, Dr. Yuh designed and conducted many clinical trials and facilitated the FDA approval of MR contrast agents, which have become essential components of current MR imaging examination. His recent research focuses on assessing tumor heterogeneity for early prediction of ultimate treatment outcome for cancer and for the collateral circulation status for triaging therapy for acute stroke.

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Steven Zeliadt , PhD, MPH

Email: szeliadt@u.washington.edu

Phone: (206) 277-4175

Dr. Zeliadt's research interests include decision-making and quality of life in prostate cancer treatment, cancer screening, costs of health care interventions, evaluation of informed decision making strategies, comparative effectiveness using large databases, quality of life assessment among cancer survivors, decision modeling, assessment of health care costs.

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Jing Zeng , MD

Email: jzeng13@uw.edu

Phone: (206) 598-5998

Dr. Zeng is a radiation oncologist who specializes in treating lung cancer, thoracic malignancies, and genitourinary tumors, including prostate cancer, using the latest technologies and available clinical trials.

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Jing Zhang , MD, PhD

Email: zhangj@u.washington.edu

Phone: (206) 897-5245

Dr. Zhang's research focus is on the use of proteomic techniques to discover novel proteins that are involved in chronic neurodegenerative diseases such as Parkinsons disease (PD) and Alzheimers disease (AD) as well as in the aging process. Dr. Zhang is a neuropathologist who specializes in diagnosing neurodegenerative diseases.

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Miqin Zhang , PhD

Email: mzhang@u.washington.edu

Phone: (206) 616-9356

Dr. Zhang's research interests include protein, cell, and biomaterial interactions; biocompatibility assessment; protein and cell micropatterning for biosensing and BioMEMS applications; biomaterials for tissue engineering and regenerative medicine; controlled drug delivery; nanotechnology for cancer diagnosis and therapy.

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Lue-Ping Zhao , PhD

Email: lzhao@fredhutch.org

Phone: (206) 667-6927

Being trained in biostatistics/bioinformatics, epidemiology and genetics, Dr. Zhao's current interest in STTR includes how to use omics methodology to dissect solid tumor etiology and mechanism with either expression arrays, SNP arrays, or short-read sequencing methods. Further, he is interested in utilizing large and complex electronic medical records with modern genomic technologies for translational bioinformatics studies.

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