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Viswam Nair , MD, MS

Email: vnair@fredhutch.org

Phone: (206) 667-4971

Dr. Viswam Nair translates fundamental scientific discoveries into the clinic to improve the care of people with lung cancer. His research focuses on biomarkers, or telltale biological markers of health or disease. He studies how to best integrate molecular and imaging-based biomarkers into clinical practice to improve lung cancer detection and treatment.

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Andrew Oberst , Ph.D.

Email: oberst@uw.edu

Phone: (206) 221-7316

Dr. Oberst's research focuses on understanding how different forms of cell death occur, and how they influence immune responses in vivo. Multicellular organisms are complex communities cooperating of cells, and the death of some cells is required for the community to survive and thrive. His work studies the effect of each type of cell death in vivo, with the goal of understanding their role in processes such as inflammation, autoimmunity, tumor suppression, and immune responses to pathogen infection.

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Kayode Ojo , PhD

Email: ojo67kk@uw.edu

Phone: (206) 543-0821

The research focus of the Ojo Lab is to develop novel, robust, safe and affordable antimicrobial agents that can withstand the threat of resistance while effectively treating debilitating parasitic diseases. They also have compounds in their drug library that could have an effect on breast, lung, melanoma and prostate cancer cells.

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Amy Paguirigan , PhD

Email: apaguiri@fredhutch.org

Phone: (206) 667-4352

The focus of my research has been the integration of emerging technologies to address clinically relevant questions in cancer biology. My focus is on the interface between clinical molecular biology, bioinformatics and biotechnology, in aiming to bridge the gaps to bring novel approaches in both the biotechnological and informatics realms to clinical molecular biology to study the role of clonal diversity in cancer therapy.

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Susan Parkhurst , PhD

Email: susanp@fredhutch.org

The Parkhurst lab is interested in the actions of both maternally and zygotically contributed gene products that govern proper embryonic development in Drosophila. Building tissues and organs during embryogenesis involves a series of exquisite morphogenetic processes including precisely orchestrated tissue contractions, foldings and migrations. Many of the naturally occurring epithelial movements that shape the embryo during morphogenesis are similar to those employed in the wound healing response and to cell behaviors in tumor progression. The Parkhurst lab uses developmental, genetic, cell biological, and molecular approaches to look at different regulatory mechanisms and pathways required for proper Drosophila embryonic development. Their current efforts are divided between studies of: (1) molecular and cellular mechanisms of single cell and multicellular (tissue) wound repair; (2) actin and microtubule cytoskeleton dynamics mediated by the Rho1 small GTPase and its effectors Wash, Capu, and Spire; and (3) nuclear architecture and organization.

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Sudhakar Pipavath , MD

Email: snjp@u.washington.edu

Phone: (206) 543-3320

Dr. Pipavath is a UW assistant professor of radiology whose clinical interests include imaging of lung diseases, including interstitial lung disease, lung cancer and acute pulmonary thromboembolism (PE). He is also conducting research on imaging of interstitial lung disease and acute PE.

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Seth Pollack , MD

Email: spollack@fredhutch.org

Phone: (206) 667-6629

Dr. Pollack is a medical oncologist who treats adult patients with sarcoma. His clinical interests include sarcoma, and immune-based therapies.

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Colin Pritchard , MD, PhD

Email: cpritch@uw.edu

Phone: (206) 598-8400

Dr. Pritchard specializes in cancer molecular diagnostics development for precision medicine and microRNA as blood-based biomarkers and he helped to develop UW-OncoPlex (a molecular test which can inform diagnosis, prognosis, and/or treatment plans for patients). His research is focused on two main areas related to cancer molecular diagnostics: microRNA as blood-based biomarkers, and cancer molecular diagnostics development for precision medicine.

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Daniel Raftery , PhD

Email: draftery@uw.edu

Phone: (206) 543-9709

Dr. Raftery is an expert in the field of metabolomics, the study of small molecules involved in the metabolism of biological systems, cells, animals and humans. His research focuses on the development of advanced analytical tools and statistical methodologies for profiling metabolites in complex biological samples. He has applied these analytic approaches and demonstrated their utility for early detection of several types of cancer, as well as their utility in researching diabetes and heart disease.

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Scott Ramsey , MD, PhD

Email: sramsey@fredhutch.org

Phone: (206) 667-7846

Dr. Ramsey is a member of the Public Health Sciences Division at Fred Hutch. His research focus is comparative effectiveness analysis; cost effectiveness analysis, health economics, and cancer outcomes research. He is a doctors and health economists who has lead studies on patterns of care, costs and cost-effectiveness of treatments for lung, colorectal and prostate cancer.

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Mary Redman , PhD

Email: mredman@fredhutch.org

Phone: (206) 667-4767

Dr. Redman's primary interests are in clinical trial designs for assessment and discovery of predictive biomarkers of targeted agents and interim monitoring considerations for hybrid designs.

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Ramesh Rengan , MD, PhD

Email: rengan@uw.edu

Phone: (206) 598-4100

Dr. Ramesh Rengan is the associate medical director at SCCA Proton Therapy, A ProCure Center. He is internationally known for his work in treating lung cancer, esophageal cancer, thoracic malignancies, and melanoma. He specializes in genitourinary tumors including prostate cancer.

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Laura Riolobos , PhD

Email: lriolobo@uw.edu

Phone: 206-221-6454

Dr. Riolobos received her PhD in Molecular Biology from Universidad Autonoma of Madrid in 2006. During her PhD she studied the nuclear transport of Parvovirus structural proteins and the capsid assembly intermediates. After graduation, she worked as a Research scientist at Protein Alternatives in Madrid where she optimized the Phage Display technology to obtain specific antibodies against colorectal cancer biomarkers. In 2010, she joined the University of Washington as a Senior Fellow in the Hematolgoy Department, her project aimed to obtain “Universal” Stem Cells that would not be recognized as allogeneic by knocking-down the B2M and HLA-I genes. Currently, Dr. Riolobos is working with the CVI on the development and characterization of vaccines for lung cancers.

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Anthony Rongvaux , PhD

Email: rongvaux@fredhutch.org

Phone: (206) 667-7753

Dr. Rongvaux's work focuses on developing models of humanized mice to study the role of the immune system in solid tumor development. His lab is transplanting mice with hematopoietic stem and progenitor cells (CD34+ cells) obtained from bone marrow or peripheral blood after G-CSF mobilization, the tumor from the same patient, and in some cases T cells isolated from peripheral blood of the donor. His team is interested in understanding how infiltrating macrophages affect tumor growth as well as the response to immunotherapies. Most of my work so far has focused on melanoma. We are now also starting projects, with collaborators on the East Coast, on breast and lung cancer.

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Joshua Roth , PhD, MHA

Email: jroth@fredhutch.org

Phone: (206) 930-5821

Dr. Roth is interested in the application of comparative effectiveness research methods to inform translation of cancer therapeutics and diagnostics, including: observational study design, decision modeling, randomized controlled trial design, systematic review, and meta-analysis.

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Walter Ruzzo , PhD

Email: ruzzo@cs.washington.edu

Phone: (206) 543-6298

Dr. Ruzzo's research is focused on development of computational methods and tools applicable to practical problems in molecular biology, an increasingly data-rich discipline. Recent work has focused on analysis of high throughput sequencing data, such as chromatin immunoprecipitation (ChIPseq) and transcriptomic (RNAseq) data, including development of new methods for mapping, assembly, bias correction, isoform quantitation, and motif discovery. New methods for finding noncoding RNA (ncRNA) genes are also being actively developed.

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Rafael Santana-Davila , MD

Email: rafaelsd@u.washington.edu

Phone: (206) 288-2190

Dr. Rafael Santana-Davila is a medical oncologist who specializes in treating lung and head and neck cancers.

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Juila Sidorova , PhD

Email: julias@u.washington.edu

Phone: (206) 543-6585

Dr. Sidorova studies DNA replication in normal and cancer-derived human cells. She uses microfluidics assisted replication track analysis, or maRTA, a DNA fiber technology, to quantify genomic replication in vivo at the level of individual replication forks. Her lab’s specific interest is in the ways replication under stress generated by DNA damaging drugs or oncogenic mutations affects genomic stability and cell survival or promotes carcinogenesis.

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Roland Strong , PhD

Email: rstrong@fredhutch.org

Phone: (206) 667-5587

Dr. Strong's lab research focuses on structural molecular immunology and vaccinology by using biophysical approaches to study proteins and interactions mediating or modulating adaptive and innate immune responses.

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Wei Sun , Ph.D.

Email: wsun@fredhutch.org

Dr. Sun's research focuses on analyzing comprehensive genomic data, such as genome-wide DNA polymorphism (e.g., genotypes of thousands to millions of SNPs, DNA copy number variations), epigenetic information (e.g., nucleosome occupancy, histone modification), mRNA/miRNA expression, protein abundance/phosphorylation, and protein-protein interaction, as well as phenotype data to identify associations with complex traits, such as human cancer.

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