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q=Colorectal

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Raymond Yeung , MD

Email: ryeung@u.washington.edu

Phone: (206) 616-6408

Dr. Yeung is a surgeon whose focus is the treatment of liver and bile duct tumors. His research focuses on the genetic mechanisms of tumorigenesis with emphasis on tumor suppressor genes and hereditary cancers. Dr. Yeung's work exploits a unique animal model of hereditary cancer to study the multi-step process of tumor development. Two such novel tumor suppressor genes of current interest relate to the disease tuberous sclerosis complex (TSC). Dr. Yeung's laboratory utilizes genetic, cell biologic and biochemical approaches to dissect the function of these genes.

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Jing Zeng , MD

Email: jzeng13@uw.edu

Phone: (206) 598-5998

Dr. Zeng is a radiation oncologist who specializes in treating lung cancer, thoracic malignancies, and genitourinary tumors, including prostate cancer, using the latest technologies and available clinical trials.

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Lue-Ping Zhao , PhD

Email: lzhao@fredhutch.org

Phone: (206) 667-6927

Being trained in biostatistics/bioinformatics, epidemiology and genetics, Dr. Zhao's current interest in STTR includes how to use omics methodology to dissect solid tumor etiology and mechanism with either expression arrays, SNP arrays, or short-read sequencing methods. Further, he is interested in utilizing large and complex electronic medical records with modern genomic technologies for translational bioinformatics studies.

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Steven Ziegler , PhD

Email: sziegler@benaroyaresearch.org

Phone: (206) 287-5657

The projects in Dr. Ziegler’s laboratory are focused on the factors that control normal immune regulation, as well as those that contribute to disease development and progression. The laboratory is currently engaged in two areas of investigation: the genes and cell populations that are involved in controlling autoimmune-type responses, and the role of epithelial cytokines (TSLP, IL-25, and IL-33) in the regulation of barrier responses to infection and allergen challenge. Finally, they have also found a novel role for TSLP in the regulation of tumor progression, and have established a program in tumor biology, including metastatic breast cancer, colitis-associated cancer and melanoma.

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