23 Search Results

q=Clinical%20Informatics

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Katherine Adams Guthrie , PhD

Email: kguthrie@fredhutch.org

Phone: (206) 667-5595

Dr. Adams Guthrie specializes in biostatistics with current interests in design, conduct, and analysis of clinical trials; biostatistics; and women's health.

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Geoffrey Baird , MD, PhD

Email: gbaird@uw.edu

Phone: (206)744-9787

Dr. Baird's clinical interests include laboratory test utilization, molecular diagnostics, proteomics and immunohistochemistry. His group has developed a new proteomic technology for biomarker discovery in a range of diseases such as malignancies, cardiovascular disorders, and inflammatory conditions. One application of their technology is to discover protein expression changes associated with non-small cell lung cancer that have implications for diagnosis and treatment.

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James (Jim) Bassingthwaighte , MD, PhD

Email: jbb2@uw.edu

Phone: (206) 685-2012

Dr. Bassingthwaighte's lab uses multiple radioactive tracers simultaneously to measure reactions of adenosine and its metabolites and to determine their rates of transport across membranes. Models describe the kinetics in a precise way, allowing us to understand the regulation. He is also the originator of the Human Physiome Project, a large-scale international program for developing databasing and biological systems modeling for understanding genomic and pharmaceutic effects on human physiology. His program is highly collaborative, involving co-investigators at a dozen U.S. universities, several in Europe, and in 14 departments at the University of Washington. Some of these are involved in the Physiome Project, in particular the Cardiome Project. The Cardiome Project, to define a functional heart in mathematical terms, extends from the biochemistry and the signaling, to the mechanics and energetics of the three-dimensional heart.

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J David Beatty , MD

Email: David.beatty@swedish.org

Phone: (206) 320-4880

Dr. Beatty's practice and academic activities have been focused on breast cancer. His clinical practice emphasizes management of patients with complex breast care and breast cancer problems. His surgical expertise includes breast biopsy, minimally invasive technology, ultrasound guided procedures, sentinel node localization and biopsy, breast conserving surgery, oncoplastic surgery, axillary preserving surgery, image guided surgery, balloon catheter placement for partial breast irradiation, bloodless surgery, and integration of surgery and multidisciplinary care.

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Karl Bohringer , PhD

Email: karlb@u.washington.edu

Phone: (206) 221-5177

Dr. Bohringer's current research interests include micromanipulation and microassembly, as well as biomedical implants and bioMEMS for single-cell genomics and proteomics. There are two major research themes in his work: Controlling surfaces and interfacial forces at the micro and nano scale, including systems for controlled self-assembly of microcomponents, programmable surfaces whose local properties (for example, hydrophobicity) can be changed on demand, and MEMS actuator arrays and microrobots for moving tiny objects; Joining MEMS and biology by integrating new biomaterials into MEMS processes and devices, biomedical sensor implants, and microfluidic chips for handling and analyzing biological samples. Dr. Bohringer is also interested in discussing ideas for leveraging the unique capabilities of the Washington Nanofabrication Facility for research programs in the biomedical field.

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Stephen Bowen , PhD

Email: srbowen@uw.edu

Phone: (206) 598-1128

Dr. Bowen's research focuses on quantitative molecular imaging of cancer and normal tissue for personalized radiation therapy. Specifically he is interested in machine learning of respiratory patterns for personalized motion management strategies during image acquisition, radiotherapy planning, and radiotherapy delivery; dose painting based on respiratory-gated FDG PET in NSCLC; and functional avoidance planning of both MAA and DTPA SPECT-defined lung regions in NSCLC and SC SPECT-defined liver regions in HCC.

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James (Jim) Brinkley , MD, PhD

Email: brinkley@u.washington.edu

Phone: (206) 543-3954

Dr. Brinkley's primary research interest is biomedical informatics - the representation, management, sharing, visualization and utilization of neuroscience data and knowledge. He is the founder of the field of Structural Informatics, which has as its goal the development of methods for representing the structure of the body at multiple levels of detail, as for using these methods for organizing and integrating biomedical information. His aim is to find ways to represent the structure or the body in computer-readable form, and find ways to associate these representations with the myriad biomedical data that are available. His goal is to provide a structural information framework for integrating a huge variety of big and small biomedical data. Dr. Brinkley's projects have included anatomy education, brain mapping through the national Human Brain Project, cardiovascular data integration, clinical trials data integration through the national Clinical translational Science Awards, radiological image annotation and integration through the RadLex project, and craniofacial malformations data integration through the national FaceBase consortium. He is also interested in developing web-accessible computer applications utilizing these representations to solve practical problems in clinical medicine, research and education.

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David Chhieng , MD, MBA, MSHI, MSEM, MA (HON)

Email: dchhieng@uw.edu

Phone: (206) 598-3315

Dr. Chhieng is director of Anatomic Pathology and a UW profession of pathology. He is surgical pathologist, with expertise in cytopathology, especially in performing and interpreting fine needle aspiration biopsy (FNA). Dr. Chhieng is board certified in Anatomic and Clinical Pathology, Cytopathology, and Clinical Informatics.

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Min Fang , MD, PhD

Email: fangm@uw.edu

Phone: (206) 288-1390

Dr. Fang's research focus is on the genomics and combinatorial genetics/epigenetics of human neoplasia. She is combining classical genetic approaches of mapping, karyotyping, and functional genetics with new genomic tools including microarray, comparative genome hybridization, and next-generation sequencing, to identify genetic and epigenetic aberrations in cancer that may serve as actionable biomarkers for treatment decision making for individual patients.

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David Fredricks , MD

Email: dfredric@fredhutch.org

Phone: (206) 667-1935

Dr. Fredricks's lab has identified several fastidious bacterial species that are useful markers of BV and are associated with adverse health outcomes. They are using novel cultivation methods to propagate some of these bacteria in the lab, and study how indigenous microbes interact with each other and the human host. He is currently looking for collaboration in molecular biology, microbiology, immunology, and cell biology. He is also looking for collaborators to focus on clinical epidemiology by studying microbial ecology in different human hosts.

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Patrick Heagerty , PhD, MS

Email: pheagert@fredhutch.org

Phone: (206) 667-2685

Dr. Heagery's research interests are Regression techniques for dependent data including marginal models and random effects models for longitudinal data, methods for categorical time series, and hierarchical models for categorical spatial data, statistical computing, and applications in epidemiology and ecology.

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Noah Hoffman , MD, PhD

Email: ngh2@uw.edu

Phone: (206) 598-7932

Dr. Hoffman's clinical interests and responsibilities include the development and application of software and processes for the collection, management, and display of data generated in the clinical laboratory. His research is focused on creating applications and algorithms to classify medically important microorganisms using biological sequence information.

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Dick Hoskins , PhD, MPH

Email: rhoskins@uw.edu

Phone: (907) 317-6821

Dr. Hokins' main interest in public health practice concerns the impact of climate change on wildlife and human health and how they interact. He is a participant in the Fulbright Specialist Program working as requested in developing countries. His specific research interests include applications of geographic information systems to public health practice, spatial statistics, and environmental hazard assessment for wildlife.

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Michael LeBlanc , PhD

Email: mleblanc@fredhutch.org

Phone: (206) 667-6089

Dr. LeBlanc's current research interests are statistical methods for clinical trials, adaptive and non-parametric regression models, and survival analysis. Some of his current projects are in the SWOG Statistical Center and Statistical Methods for Clinical Studies.

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Amy Paguirigan , PhD

Email: apaguiri@fredhutch.org

Phone: (206) 667-4352

The focus of my research has been the integration of emerging technologies to address clinically relevant questions in cancer biology. My focus is on the interface between clinical molecular biology, bioinformatics and biotechnology, in aiming to bridge the gaps to bring novel approaches in both the biotechnological and informatics realms to clinical molecular biology to study the role of clonal diversity in cancer therapy.

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Thomas Payne , MD

Email: tpayne@uw.edu

Dr. Payne’s major professional interest is the use and evaluation of clinical computing systems, especially electronic health records (EHRs) in patient care, clinical research, and quality improvement. Most of his work since completing his fellowship has involved development, selection, installation and operation of EHRs. His research interests include electronic documentation, natural language processing, and operating clinical computing programs.

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Brian Shirts , MD, PhD

Email: shirtsb@uw.edu

Phone: (206) 598-0557

Dr. Shirt's research focuses on integrating complex genetics knowledge into clinical care. There are several related aspects of this research: clinical classification of rare variants, particularly variants in familial cancer genes; improving the use of complex and multi-factorial clinical information, with special interest in personalized healthcare using genetic information; and storage and communication of genetic information in the health care setting (including formatting genetic test results so that they are searchable in clinical laboratory information systems and so that electronic health records can use genetics to provide active decision support).

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Kari Stephens , PhD

Email: kstephen@uw.edu

Phone: (206) 221-0349

Dr. Stephens conducts research related to dissemination of evidenced base practices addressing mental health care and the leveraging of methods and tools focused on use of electronic health data to improve care. Her clinical expertise includes cognitive and behavioral based psychotherapy, including treatments for depression, anxiety, trauma, addiction, and chronic pain.

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Peter Tarczy-Hornoch , MD, FACMI

Email: pth@u.washington.edu

Phone: (206) 685-8093

Dr. Tarczy-Hornoch's current research focuses on data integration of biomedical and health data. This includes looking at ways of handling semi structured data, representing uncertainty at various levels in the system, and doing computerized reasoning over integrated data. The main problems he is focusing on are large scale functional gene annotation of bacteria and protozoans; single-nucleotide polymorphisms for elucidation of disease mechanisms; expression array experiment analysis; and research in the area of collaborative integrated analysis of a combination of clinical data, experimental biological data, and clinical/translational research study data.

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