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q=Collaboration

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Neil Abernathy , PhD

Email: neila@u.washington.edu

Phone: (206) 616-2813

Dr. Abernathy's current research interests are public health informatics standards, epidemic models, and molecular epidemiology in the context of global health; scientific and social networks as they pertain to collaborative research; novel 3-D imaging displays; Environmental interventions for infectious disease; high-throughput biology; and evolutionary game theory.

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Katherine Adams Guthrie , PhD

Email: kguthrie@fredhutch.org

Phone: (206) 667-5595

Dr. Adams Guthrie specializes in biostatistics with current interests in design, conduct, and analysis of clinical trials; biostatistics; and women's health.

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Niels Andersen , PhD

Email: andersen@chem.washington.edu

Phone: (206) 543-7099

Dr. Anderson's research team focuses on both the fundamental thermodynamics and structural features associated with biorecognition phenomena and practical applications in drug and protein design. The primary biophysical tools employed are spectroscopic: NMR determinations of polypeptide structure and dynamics, IR- and fluorescence-monitored T-jump kinetics for folding pathways, CD studies of the melting of secondary and tertiary structure. His drug design efforts are supported by NMR structural data for protein hormones and enzymes for key steps required for the viability of bacteria.

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Steve Andrews , PhD

Email: sandrews@fredhutch.org

Phone: (206) 667-7007

Dr. Andrews's research is in the interdisciplinary field of systems biology. His interests are in the combination of physics, chemistry, and biology methods to investigate organization within biological systems, on size scales that typically range from a few proteins to many cells. Results are yielding insights into how the highly structured macroscopic world of living organisms is built from the stochastic microscopic world of individual molecules. He is also providing an improved conceptual foundation for medical and biotechnology developments, with impacts on topics such as drug discovery, personalized medicine, biofuel generation, and bioremediation.

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Cecilia Aragon , PhD

Email: aragon@uw.edu

Phone: (206) 543-2567

Dr. Aragon's current research focuses on visual analytics, data science, collaborative creativity, emotion in text communication, text analytics, and the study of socio-technical systems including online text communication and social media. Her research group both develops software for and produces qualitative studies relating to the socio-technical aspects of data science with a focus on very large text data sets. Some of her other projects include the use of computer gaming for collaborative science and engineering learning and discovery, and topics related to usability and sustainability.

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Wyeth Bair , PhD

Email: wyeth0@uw.edu

Phone: (206) 221-8241

Dr. Bair's group integrates computational modeling and electrophysiology to study neural coding and cortical circuitry in the visual system. A primary focus of his work is the visual motion pathway. He is currently developing several integrated online resources to carry out his goals. These include the Neural Signal Archive, which contains neuronal data for public access; the Working Models site, which provides access to network models of the visual system; and the data system, which is a set of utilities for storing and analyzing spike trains.

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Geoffrey Baird , MD, PhD

Email: gbaird@uw.edu

Phone: (206)744-9787

Dr. Baird's clinical interests include laboratory test utilization, molecular diagnostics, proteomics and immunohistochemistry. His group has developed a new proteomic technology for biomarker discovery in a range of diseases such as malignancies, cardiovascular disorders, and inflammatory conditions. One application of their technology is to discover protein expression changes associated with non-small cell lung cancer that have implications for diagnosis and treatment.

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Magdalena (Magda) Balazinska , PhD

Email: magda@cs.washington.edu

Phone: (206) 616-1069

Dr. Balazinska's research interests are in the field of database management systems. Her current research focuses on big data management, scientific data management, and cloud computing.

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Nitin Baliga , PhD

Email: nbaliga@systemsbiology.org

Phone: (206) 732-1266

Dr. Baliga leads a group which builds predictive models of complex biological phenomena that can be used to guide cells in the fight against disease, they have established numerous collaborations to apply this methodology to wide-ranging problems from climate change to cancer. In ongoing research, Dr. Baliga is applying advanced methods to the study of brain cancer (glioblastoma multiforme) to gain insights into human disease to improve prevention, diagnosis, prognosis and treatment.

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Aasthaa Bansal , PhD

Email: abansal@uw.edu

Phone: (206) 427-5448

Dr. Bansal's research interests include the statistical evaluation of biomarkers and medical tests for disease prognosis and treatment selection. In addition to her background developing statistical methodology, she was involved in collaborative research at the Center for Biomedical Statistics from 2009 to 2013. While there, Bansal worked with academic investigators on the statistical analysis of studies in colon cancer screening, esophageal cancer treatment, institutional profiling, chronic illness management and juvenile arthritis.

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James (Jim) Bassingthwaighte , MD, PhD

Email: jbb2@uw.edu

Phone: (206) 685-2012

Dr. Bassingthwaighte's lab uses multiple radioactive tracers simultaneously to measure reactions of adenosine and its metabolites and to determine their rates of transport across membranes. Models describe the kinetics in a precise way, allowing us to understand the regulation. He is also the originator of the Human Physiome Project, a large-scale international program for developing databasing and biological systems modeling for understanding genomic and pharmaceutic effects on human physiology. His program is highly collaborative, involving co-investigators at a dozen U.S. universities, several in Europe, and in 14 departments at the University of Washington. Some of these are involved in the Physiome Project, in particular the Cardiome Project. The Cardiome Project, to define a functional heart in mathematical terms, extends from the biochemistry and the signaling, to the mechanics and energetics of the three-dimensional heart.

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J David Beatty , MD

Email: David.beatty@swedish.org

Phone: (206) 320-4880

Dr. Beatty's practice and academic activities have been focused on breast cancer. His clinical practice emphasizes management of patients with complex breast care and breast cancer problems. His surgical expertise includes breast biopsy, minimally invasive technology, ultrasound guided procedures, sentinel node localization and biopsy, breast conserving surgery, oncoplastic surgery, axillary preserving surgery, image guided surgery, balloon catheter placement for partial breast irradiation, bloodless surgery, and integration of surgery and multidisciplinary care.

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Trevor Bedford , PhD

Email: tbedford@fredhutch.org

Phone: (206) 667-6372

Dr. Bedford studies the dynamics of virus populations. This includes the questions of how strains spread through the world, strains evolve in response to immune pressure, and ultimately what makes a strain successful.

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Shirley Beresford , PhD, MSc, MA

Email: beresfrd@u.washington.edu

Phone: (206) 543-9512

Dr. Beresford's research interests are in the areas of nutritional epidemiology and chronic disease prevention; specifically designed to improve the scientific basis for public health policy and recommendations concerning dietary intake, physical activity and intake of folic acid.

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Slobodan Beronja , PhD

Email: beronja@fredhutch.org

Phone: (206) 667-7609

Dr. Beronja's group studies molecular and cellular mechanisms essential for tissue growth during development and the formation of tumors. His goal is to identifying genes and gene pathways that can be used as targets in cancer therapy.

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Parveen Bhatti , PhD

Email: pbhatti@fredhutch.org

Phone: (206) 667-7803

Dr. Bhatti's research focus is on occupational and environmental epidemiology of cancer with a focus in biomarkers of exposure, susceptibility and disease; particularly genetic susceptibility to cancer following low dose exposure to occupational or medical ionizing radiation.

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Mark Binder , PhD

Email: mdbinder@uw.edu

Phone: (206) 543-2509

Dr. Binder's lab is presently investigating the dendritic mechanisms affecting the transfer of synaptic current to the soma of hypoglossal motoneurons recorded in rat brainstem slices. His team studies the voltage-dependance of the synaptic currents, what types of voltage-gated conductances on the dendrites affect the transfer of current to the soma and how concurrently-activated synaptic currents interact. They also use fluorescent imaging to determine the spatial distribution of the dendritic sodium, calcium, and mixed-cation channels. Binder's experimental projects are complemented by computer simulations using compartmental models of motoneurons with different types and distributions of dendritic conductances to help interpret the experimental data.

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C. Anthony (Tony) Blau , MD

Email: tblau@u.washington.edu

Phone: (206) 685-6873

Dr. Blau specializes in orchestrating collaborations across disparate scientific disciplines toward grand goals. As a physician-scientist he believes that our approach to cancer needs to be fundamentally restructured, and for this reason founded the UW's Center for Cancer Innovation (CCI). CCI applies the latest scientific knowledge to the treatment of today's cancer patients while using their experiences to benefit all cancer patients tomorrow. CCI recently launched its first clinical trial in an aggressive form of breast cancer called 'triple-negative' breast cancer. CCI is a grass-roots 'coalition of the willing,' comprised of nearly 100 community and academic oncologists, scientists, computational biologists, and other specialists from six different organizations, and owes much of its success to support from the South Sound region.

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Jesse Bloom , PhD

Email: jbloom@fredhutch.org

Phone: (206) 667-3622

Dr. Bloom studies the molecular evolution of proteins and viruses. Rapid evolution is a defining feature of many of the most medically problematic viral diseases, including influenza. Although this rapid evolution is usually bad from the perspective of public health, it offers a unique vantage from which to study a range of important questions in biology. His group takes an evolutionary perspective as we use a combination of experimental and computational techniques to study questions in virology, immunology, and protein biochemistry.

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