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Smith (Jim) Apisarnthanarax , MD

Email: apisarn@uw.edu

Phone: (206) 598-4100

Dr. Apisarnthanarax is a radiation oncologist with clinical expertise in gastrointestinal cancers and genitourinary tumors, including the use of proton radiation to treat these cancers. Dr. Apisarnthanarax's research interests include optimizing the treatment of liver cancers, integrating proton beam radiation therapy into the multidisciplinary care of cancer, and using novel functional imaging to personalize cancer care by decreasing normal tissue toxicity and assessing cancer treatment response.

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David Au , MD, MS

Email: dau@uw.edu

Phone: (206) 764-2430

Dr. Au's research focuses on improving the quality and delivery of care for patients with chronic lung diseases, in particular, he is interested in primary pulmonary manifestations of tobacco smoke; COPD and lung cancer. His primary research focuses is on identifying and intervening upon potential gaps in the quality of care for patients with lung cancer and COPD. These gaps include a focus on the quality of end-of-life communication and care, delivery of high quality palliative care, heterogeneity in care, and whether health care delivery is concordant with best available evidence.

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Mike Averkiou , PhD

Email: maverk@uw.edu

Phone: (206) 616-9558

Dr. Averkiou develops new ultrasound imaging and therapy technology for disease detection, improved cancer treatment and monitoring, improved drug delivery to targeted cells, and heart disease. Using advanced nonlinear imaging techniques and microbubble contrast agents, he is able to detect the earliest stages of tumor angiogenesis and atherosclerosis, and closely monitor their treatment. He focuses on transferring innovations from preclinical research into clinical use.

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Anthony Back , MD

Email: tonyback@u.washington.edu

Phone: (206) 288-6426

Dr. Back is a medical oncologist who specializes in treating cancers of the gastrointestinal system. Dr. Back also treats patients at SCCA. His patients include people with colorectal, liver, pancreatic, and stomach cancer. He is an expert in communication between physicians and patients and has published a number of papers on this topic.

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Tania Bardyn , MLIS, AHIP

Email: bardyn@uw.edu

Phone: (206) 543-0422

Ms. Bardyn's research has focused on evaluating the information needs of clinicians and translational researchers in various disciplines; how to deliver information programs and librarian services to develop collaborative partnerships and library buildings and space planning.

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Kevin Barry , PhD

Email: kbarry@fredhutch.org

Phone: (206) 667-7811

Dr. Barry aims to determine how innate immune cells recognize cancer and regulate immune responses. He previously identified a novel set of immune cells that regulate immune responses that protect patients from melanoma. The number of these cells in a patient’s tumor can identify those patients who will benefit the most from immunotherapy. Dr. Barry and his team are learning more about the signals that control this set of innate immune cells in cancer. His goal is to generate novel therapies to increase cancer-killing immune responses and save lives from cancer.

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Stephen Bowen , PhD

Email: srbowen@uw.edu

Phone: (206) 598-1128

Dr. Bowen's research focuses on quantitative molecular imaging of cancer and normal tissue for personalized radiation therapy. Specifically he is interested in machine learning of respiratory patterns for personalized motion management strategies during image acquisition, radiotherapy planning, and radiotherapy delivery; dose painting based on respiratory-gated FDG PET in NSCLC; and functional avoidance planning of both MAA and DTPA SPECT-defined lung regions in NSCLC and SC SPECT-defined liver regions in HCC.

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Susan Bullman , PhD

Email: sbullman@fredhutch.org

Phone: (206) 667-3449

The Bullman Lab focuses firstly on understanding the translational impact of the tumor microbiota in human cancers, and secondly on the delineation of specific mechanisms involved in the pathogenesis of microbe-associated human cancers. They combine molecular microbiology, computational biology, biochemistry, and genetics to understand host-microbial interactions within the tumor microenvironment. Through such efforts, her lab seeks to make discoveries that have both a scientific and clinical impact in the emerging area of bacterial-associated malignancies. Bacterial agents that have a role in cancer initiation or progression provide a viable route for prevention and treatment of these cancers.

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Stacey Cohen , MD

Email: shiovitz@uw.edu

Phone: (206) 667-5702

Dr. Shiovitz is a medical oncologist who specializes in treating people with colorectal and other gastrointestinal cancers. Her areas of expertise include colorectal cancer, early onset cancer, hereditary cancers, and gastrointestinal cancers

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Cole DeForest , PhD

Email: ProfCole@uw.edu

Phone: (206) 543-5961

The DeForest Group seeks to integrate the governing principles of rational design with fundamental concepts from material science, synthetic chemistry, and stem cell biology to conceptualize, create, and exploit next-generation materials to address a variety of health-related problems. They are currently interested in the development of new classes of user-programmable hydrogels whose biochemical and biophysical properties can be tuned in time and space over a variety of scales. Their work relies heavily on the utilization of cytocompatible bioorthogonal chemistries, several of which can be initiated with light and thereby confined to specific sub-volumes of a sample. By recapitulating the dynamic nature of the native tissue through 4D control of the material properties, these synthetic environments are utilized to probe and better understand basic cell function as well as to engineer complex heterogeneous tissue.

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Manjiri Dighe , MD, FSAR, FSRU

Email: dighe@uw.edu

Phone: 206-598-0024

Dr. Dighe is section chief of body imaging at the University of Washington and a UW associate professor of radiology. In addition to body imaging, she is an expert in obstetric and thyroid imaging. She also conducts research on thyroid nodules using non-invasive ways to diagnose malignancy which includes ultrasound elastography. She also has a long interest and expertise in obstetric imaging and works closely with the Maternal Fetal Medicine group in UW to diagnose complex cases.

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Jason Dominitz , MD, MHS

Email: dominitz@u.washington.edu

Phone: (206) 764-2285

Dr. Dominitz is a gastroenterologist whose clinical expertise is colorectal cancer screening; colonoscopy and polyp removal. His research interests include outcomes research in gastroenterology with specific interest in the epidemiology of gastrointestinal and liver disease.

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Taran Gujral , PhD, Msc

Email: tgujral@fredhutch.org

Phone: (206) 667-4149

Cells respond to external stimuli by activating nonlinear and highly interconnected networks of signaling proteins. Dr. Gujral's work focuses on understanding how these networks are wired in different cell types and how they influence response to growth factors or cytotoxic agents using both hypothesis driven and systems-based data-driven approaches. His lab combines approaches from molecular genetics with cell and systems biology to study a recently discovered Wnt5-Fzd2 signaling pathway in metastasis as well as cell-to-cell contact in regulating cell fate decisions.

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George Ioannou , B.M.B.Ch, MS, FAASLD

Email: George.Ioannou@va.gov

Dr. Ioannou's clinical and research interests include liver cancer, hepatitis C, non-alcoholic fatty liver disease, iron deficiency and iron overload.

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Elizabeth Krakow , MD

Email: efkrakow@fredhutch.org

Phone: (206) 667-3410

Dr. Krakow is interested in using HLA-mismatched non-engrafting cell therapy to treat cancer. The goal is to avoid graft-versus-host disease and long-term immunosuppression, but still harness transient benefits of direct alloreactivity while restoring the recipient (or original donor) immune system’s cancer surveillance and eradication mechanisms. She also studies how to deliver personalized recommendations for sequences of chemo/immunotherapies.

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Sharon Kwan , MD

Email: shakwan@uw.edu

Phone: (206) 543-5972

Dr. Kwan is an interventional radiologist. She performs minimally invasive procedures using image-guidance, with a clinical focus in the treatment of liver cancer and uterine fibroids. Dr. Kwan's research interests include healthcare utilization, comparative effectiveness, hepatocellular carcinoma, transarterial chemoembolization; Y-90 radioembolization and transjugular intrahepatic portosystemic shunts.

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Jean Lee , MD

Email: jeanhlee@u.washington.edu

Phone: (206) 598-0023

Dr. Lee is a radiologist who specializes in imaging for high-risk localized prostate cancer. Her clinical expertise is in prostate imaging, hepatobiliary, pancreatic and transplant imaging.

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Yawen Li , PhD

Email: liyw@uw.edu

Phone: (206) 616-8518

Dr. Li is interested in therapeutic and diagnostic radiopharmaceuticals, astatine labeling reagents for small molecule labeling, and developing chemical methods for separation of high specific activity medical radionuclides.

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Wayne Monsky , MD, PhD

Email: wmonsky@uw.edu

Phone: 206 598-1454

Dr. Monsky is director of interventional radiology at the Harborview Medical Center and also provides clinical care at the UW Medical Center. He is a UW associate professor of radiology. He is an expert in all aspects of interventional radiology including minimally invasive therapies for cancer, uterine fibroids, deep venous thrombosis, and gastrointestinal bleeding. He also conducts research on novel approaches to treat solid malignancies, remove blood clots and the use of advanced ultrasound techniques to diagnose and treat a number of diseases, as a member of the Ultrasound-based Washington Molecular Imaging and Therapy Center. He has been integral to the development and optimization of a number of state-of-the-art novel medical devices.

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Beth Mueller , DrPH

Email: bmueller@fredhutch.org

Phone: (206) 667-4903

Dr. Mueller studies the roles of maternal, gestational, and early life factors and early environmental exposures in the occurrence of childhood cancer and autoimmune diseases. Her studies include: reproductive history in relation to cancer and cancer survival in women; reproductive outcomes among male and female childhood cancer survivors; maternal, gestational, and early life factors and early environmental exposures in relation to reproductive outcomes such as malformations, fetal death, low birth weight, and preterm delivery; and improving exposure assessment methods in epidemiologic studies of prenatal and childhood exposures.

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