92 Search Results

q=Programmatic%20ideas

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Shreeram Akilesh , MD, PhD

Email: shreeram@uw.edu

Phone: (206) 598-6408

Dr. Akilesh is presently applying next generation genomic tools and analyses to understand the development, structure and function of the kidney and its component cells in health and disease.

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Wyeth Bair , PhD

Email: wyeth0@uw.edu

Phone: (206) 221-8241

Dr. Bair's group integrates computational modeling and electrophysiology to study neural coding and cortical circuitry in the visual system. A primary focus of his work is the visual motion pathway. He is currently developing several integrated online resources to carry out his goals. These include the Neural Signal Archive, which contains neuronal data for public access; the Working Models site, which provides access to network models of the visual system; and the data system, which is a set of utilities for storing and analyzing spike trains.

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Nitin Baliga , PhD

Email: nbaliga@systemsbiology.org

Phone: (206) 732-1266

Dr. Baliga leads a group which builds predictive models of complex biological phenomena that can be used to guide cells in the fight against disease, they have established numerous collaborations to apply this methodology to wide-ranging problems from climate change to cancer. In ongoing research, Dr. Baliga is applying advanced methods to the study of brain cancer (glioblastoma multiforme) to gain insights into human disease to improve prevention, diagnosis, prognosis and treatment.

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Brittany Barber , MD, MSc, FRCSC

Email: bbarber1@uw.edu

Dr. Barber's clinical interests include head and neck cancer surgery, robotic surgery, and salivary and endocrine surgery. She has a special interest in reconstructive surgery for skin cancers. Her research interests include quality improvement in free flap reconstruction, peripheral nerve regeneration, cancer genomics, and HPV-related oropharyngeal cancer treatment.

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Kevin Barry , PhD

Email: kbarry@fredhutch.org

Phone: (206) 667-7811

Dr. Barry aims to determine how innate immune cells recognize cancer and regulate immune responses. He previously identified a novel set of immune cells that regulate immune responses that protect patients from melanoma. The number of these cells in a patient’s tumor can identify those patients who will benefit the most from immunotherapy. Dr. Barry and his team are learning more about the signals that control this set of innate immune cells in cancer. His goal is to generate novel therapies to increase cancer-killing immune responses and save lives from cancer.

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Parveen Bhatti , PhD

Email: pbhatti@fredhutch.org

Phone: (206) 667-7803

Dr. Bhatti's research focus is on occupational and environmental epidemiology of cancer with a focus in biomarkers of exposure, susceptibility and disease; particularly genetic susceptibility to cancer following low dose exposure to occupational or medical ionizing radiation.

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Hamid Bolouri , PhD

Email: hbolouri@fredhutch.org

Phone: (206) 667-2748

Dr. Bolouri is interested in understanding how gene regulatory interactions control cellular state and identity, both in normal development and in diseases such as cancer. A particular focus of his lab is the development and use of integrative computational systems biology methods to map gene regulatory networks from whole genome data: currently they are working on identification of cis-regulatory sequence variations in childhood Acute Myeloid Leukemia.

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Stephen Bowen , PhD

Email: srbowen@uw.edu

Phone: (206) 598-1128

Dr. Bowen's research focuses on quantitative molecular imaging of cancer and normal tissue for personalized radiation therapy. Specifically he is interested in machine learning of respiratory patterns for personalized motion management strategies during image acquisition, radiotherapy planning, and radiotherapy delivery; dose painting based on respiratory-gated FDG PET in NSCLC; and functional avoidance planning of both MAA and DTPA SPECT-defined lung regions in NSCLC and SC SPECT-defined liver regions in HCC.

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Roger Brent , PhD

Email: rbrent@fredhutch.org

Phone: (206) 667-1482

Dr. Brent studies the quantitative operation of the systems that living cells use to sense, represent, transmit, and act upon information to make decisions that determine their future fates. He specifically studies prototypic cell signaling systems in budding yeast and the pheromone response system; he has extended similar work to systems operating in single cells of tissues in a metazoan, Caenorhabditis elegans.

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Susan Bullman , PhD

Email: sbullman@fredhutch.org

Phone: (206) 667-3449

The Bullman Lab focuses firstly on understanding the translational impact of the tumor microbiota in human cancers, and secondly on the delineation of specific mechanisms involved in the pathogenesis of microbe-associated human cancers. They combine molecular microbiology, computational biology, biochemistry, and genetics to understand host-microbial interactions within the tumor microenvironment. Through such efforts, her lab seeks to make discoveries that have both a scientific and clinical impact in the emerging area of bacterial-associated malignancies. Bacterial agents that have a role in cancer initiation or progression provide a viable route for prevention and treatment of these cancers.

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Roger Bumgarner , PhD

Email: rogerb@u.washington.edu

Phone: (206) 732-6137

Dr. Bumgarner's research is focused on the creation of tools to connect expression data to biological meaning and the application of these tools to understanding host-virus interactions and the host innate immune response.

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Victor Chow , MD

Email: vchow@fredhutch.org

Phone: (206) 667-7731

Dr. Chow conducts clinical research in lymphoma utilizing combination approaches with cellular-based therapies.

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Cole DeForest , PhD

Email: ProfCole@uw.edu

Phone: (206) 543-5961

The DeForest Group seeks to integrate the governing principles of rational design with fundamental concepts from material science, synthetic chemistry, and stem cell biology to conceptualize, create, and exploit next-generation materials to address a variety of health-related problems. They are currently interested in the development of new classes of user-programmable hydrogels whose biochemical and biophysical properties can be tuned in time and space over a variety of scales. Their work relies heavily on the utilization of cytocompatible bioorthogonal chemistries, several of which can be initiated with light and thereby confined to specific sub-volumes of a sample. By recapitulating the dynamic nature of the native tissue through 4D control of the material properties, these synthetic environments are utilized to probe and better understand basic cell function as well as to engineer complex heterogeneous tissue.

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Deborah Donnell , PhD

Email: deborah@scharp.org

Phone: (206) 667-5661

Dr. Donnell is a Principal Staff Scientist in the Vaccine and Infectious Disease Institute (VIDI). She is the Principal Investigator of the HIV Prevention Trials Network Statistical and Data Management Center. The scientific faculty, drawing from the University of Washington Biostatistics department and the Population Sciences Program in VIDI, are responsible for the design and analysis of Phase III clinical trials to access the efficacy of biomedical and behavioral interventions to prevent the transmission of HIV

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Adam Drewnowski , PhD

Email: adamdrew@u.washington.edu

Phone: (206) 543-8016

Dr. Drewnowski's interests are in the characterization of dietary patterns, nutrition economics, spatial distribution of obesity rates; and in the development of new metrics to identify foods that are nutrient dense, affordable and sustainable. He currently examines social determinants of health, focusing on the mechanisms behind the observed social gradient in diet quality and body weight. He has developed new methods to estimate monetary costs of individual diets, opening the door to new research on diet quality in relation to diet cost; and his studies on healthy food access make use of GIS techniques and new methods on spatial epidemiology to determine who shops for food where, why, how far from home and for how much.

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Zhijun Duan , PhD

Email: zjduan@uw.edu

Phone: (206) 543-3363

Dr. Duan's research is focused on the relationship between the form and function of human genomes during development and tumorigenesis. One of the striking features of the eukaryotic nucleus is that chromosomes adopt preferred conformations that vary across different tissues and developmental stages.

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Marianne Dubard-Gault , MD, MS

Email: mdg2019@uw.edu

Dr. Dubard-Gault is the medical director of the Cancer Genetics Program at SCCA. Her main research interest is to better understand how genetic information influences patients’ decision-making about health care and life choices. She is also interested in exploring ways to help people better access medical genetic information, talk about it with their families and use that knowledge to make decisions that fit their goals.

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Keith Eaton , MD, PhD

Email: kdeaton@u.washington.edu

Phone: (206) 288-7485

Dr. Eaton applies expert research knowledge to treating patients with lung cancer. His clinical expertise is in the areas of lung cancer, head and neck cancer, thyroid cancer, and cancer of unknown primary. His research interests include Immunotherapy and Targeted Therapies.

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