Hans-Peter Kiem MD, PhD



Bio


Dr. Kiem is experienced in pre-clinical and clinical studies involving stem cell biology including hematopoietic stem cell transplantation, gene therapy, and, more recently, induced pluripotent stem cells. As the Director of the preclinical and clinical vector program, Dr. Kiem is an expert in the generation and production of most viral and nonviral gene transfer techniques. His group has developed many different retroviral vectors and developed optimized lentivirus-mediated gene transfer conditions for hematopoietic stem cells. Dr. Kiem's research focus has been the study of stem cell biology and cell engineering with applications involving genetic and infectious diseases, such as HIV, and cancer, in particular glioblastoma. He also has extensive experience in studying stem cell biology and his pioneering work in gene transfer in large animal models, including the nonhuman primate model of AIDS, has led to several successful gene and stem cell therapy trials. Dr. Kiem also has significant knowledge in induced pluripotent stem cells (iPSCs), especially using nonhuman primate iPSCs, which hold a promising potential for improving safety in model human applications for the treatment blood stem cell and bone marrow related diseases.

Institution


Fred Hutch Transplantation Biology Associate Director
Fred Hutch Clinical Research Professor
University of Washington School of Medicine Medical Oncology Professor
University of Washington School of Medicine Pathology Adjunct Professor