Patrick Paddison PhD



Functional genomics , genomics/genetics , epigenetics , transcriptomics , splicing , mitosis , cell cycle , differentiation , hematopoiesis , miRNA , chromatin structure (histones, centromere, telomere) , regulatory networks , signaling pathways , high throughput screens

Bio


Dr. Paddison's primary goal is to define the biological units of self-renewal, expansion, and lineage commitment in model stem cell systems, including: embryonic stem cells, hematopoietic stem cells, neural progenitor cells, and brain tumor initiating cells (i.e., brain tumor stem cells). His lab uses functional genomics to probe the underlying biology of mammalian stem and progenitor cells. Specifically, they are looking at glioblastoma as a model cancer system.

Institution


Fred Hutch Human Biology and Clinical Research Professor