Ann Roman PhD

Cell Cycle , Differentiation , DNA Damage/Repair , Regulatory Networks , Pathogen , Signaling Pathways , Virus


Dr. Roman’s main focus is on the mechanism of HPV pathogenecity, addressing the interplay between the virus and its host cell in undifferentiated and differentiated conditions. She primarily studies this in low-risk HPV, those causing benign disease, to better understand what is needed for replication of all HPVs versus what is unique to the high-risk HPVs, those that contribute to the development of anogenital cancers. She also studies the impact of high-risk HPV gene products on angiogenesis, the recruitment of a blood supply to the cells expressing these viral genes.


Fred Hutch Human Biology Visiting Investigator